Difference between Xylocard , Xylocaine and Xylocaine with Adrenaline

 

Xylocard vs Xylocaine vs Xylocaine with Adrenaline 

Xylocard , Xylocaine and Xylocaine with Adrenaline are the different types of preparation of LIGNOCAINE  . They have different use , different routes of drug administration and dose .

1. Xylocard  ( also known as Loxicard ) :

contents of xylocard

loxicard

 Xylocard comes in 50 ml vial in the concentration of 2 % .

It is for single use only  as there is no preservative . 

Routes of drug administration  : Intravenous  ( I.V. )

Contents : 

1. Lignocaine Hydrochloride 21.3 mg 

2. Sodium Chloride 6.0 mg 

3. water 

Use :

1. Xylocard is given before inducing the patient with propofol as it reliefs the pain that is caused by propofol . 

2. It is also given in patients with hypertension and heart disease to prevent tachycardia caused by  laryngoscopy  and intubation .

3. to prevent intra operative arrhythmia  .

4. it is also prescribed for ventricular tachycardia with pulse . ( in larger doses as continuous infusion is required in those )

Dose :

4.4 mg/kg body weight 

should not exceed (300 mg )

Contraindication :

Stokes-Adams syndrome, or severe degrees of sinoatrial, atrioventricular or
intraventricular block 

2. Xylocaine :

XYLOCAINE 

  

Xylocard comes in 30 ml vial with 2 % preparation . 

It contains Methylparaben  as preservative so it can be used multiple times 

Routes of drug administration  : Intramuscular (I.M. )

Contents : 

CONTENTS OF XYLOCAINE 

1. Lignocaine Hydrochloride 21.3 mg 

2. Sodium Chloride 6.0 mg 

3. Methylparaben 1.0 mg 

4. water 

Use :

1. It is used as Local Anesthetic to relief the pain from a particular part of the body where any surgical interventions are made .

DOSE : SIMILAR TO XYLOCARD 

3. Xylocaine with Adrenaline :

XYLOCAINE WITH ADR

Xylocaine with Adrenaline come in 30 ml vial with 2 % preparation .

it can be used multiple times as it also contains methylparaben as preservative .

it also contains Adrenaline which causes  vasoconstriction  which result in prolong effect , less blood loss and less systemic toxicity .

but it should not be used in end organs like finger , nose tip etc. 

Routes of drug administration  : USED IN NERVE BLOCKS 

IT SHOULD NEVER BE GIVEN THROUGH I.V. 

Contents : 

CONTENTS OF XYLOCAINE WITH ADR

1. Lignocaine Hydrochloride 21.3 mg 

2. Sodium Chloride 6.0 mg 

3. Methyparaben 1.0 mg 

4. Adrenaline bitartrate 0.009 mg   ( equivalent to adrenaaline 0.005 mg )

5. Sodium metabisulphite  0.5 mg 

USE :

1. it is used in nerve blocks .

Dose :  

as it causes vasoconstriction hence less systemic absorption  so higher dose can be given .

Lignocaine with adr dose :  7mg/kg body weight  ( should not exceed 500 mg )

now as we know this drug also contains adrenaline so we also have drug dose of adrenaline  too

which is : 0.2 mg for Normal Patient 

                0.04 mg for patient with clinically significant cardio vascular disease . 

CONFUSED ?????

LET ME CLEAR YOUR DOUBT 

AS I HAVE TOLD YOU TWO DRUG DOSE ( of two different drugs  )  SO WE WILL APPLY THE CRITERIA OF DOSE BY  SEEING THE CONDITION OF PATIENT .

in normal patient maximum dose of  Xylocard is applied 

  where as in cardiovascular disease patient   maximum dose of adrenaline is applied .

Contraindication :

1. Not given in ischemic Heart Disease 

2. not given in End organs like finger , ear lobe , nose tip etc. 

SUMMARY :

1.  XYLOCARD IS A DRUG WHICH IS GIVEN THROUGH IV WHERE AS XYLOCAINE CAN NOT BE GIVEN INTRAVENOUSLY .

2. XYLOCARD  IS SINGLE USE AS IT DONT HAVE PRESERVATIVE WHEREAS XYLOCAINE AND XYLOCAINE WITH ADR  CAN BE USED MULTIPLE TIME AS THEY HAVE METHYPARABEN AS PRESERVATIVE IN THEM . 

3. XYLOCARD CAN BE USED IN THE PLACE OF XYLOCAINE BUT XYLOCAINE CANNOT BE USED IN THE PLACE OF XYLOCARD .

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